Modelling the HRF (not only timed averages) - waveform analysis #12
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Similar to what is reported in the link, could we run waveform analysis to get things like:
Area under the curve (AUC): Integral of the HbO/HbR signal over a specified time window. Captures both amplitude and duration of the response.
Cumulative HbO / HbR response: Sometimes reported as total oxygenation or "oxygenation index" (HbO – HbR).
Time-to-peak (TTP): Time from stimulus onset to maximum HbO (or minimum HbR).
Full-width at half-maximum (FWHM): Duration the response stays above half its peak.
Slope: Rate of increase in HbO during the rising phase.
Recovery slope: Rate of return to baseline after peak.
Onset latency: When the signal first rises significantly above baseline.
From my reading we want the two MNE documentations BUT the actual calculations we may have to get from source papers.
https://mne.tools/mne-nirs/stable/auto_examples/general/plot_16_waveform_group.html
https://mne.tools/mne-nirs/stable/auto_examples/general/plot_15_waveform.html (this is the MNE link)
https://pmc.ncbi.nlm.nih.gov/articles/PMC8826368/#Sec7 (this is a paper that uses some of these measures in fNIRS in a clinical setting)